Wang Yao Selected Research

Hypoxia (Hypoxemia)

2/2022	Nitric oxide nano-prodrug platform with synchronous glutathione depletion and hypoxia relief for enhanced photodynamic cancer therapy.
12/2020	Insulin-like growth factor-I prevents hypoxia-inducible factor-1 alpha-dependent G1/S arrest by activating cyclin E/cyclin-dependent kinase2 via the phoshatidylinositol-3 kinase/AKT/forkhead box O1/Cdkn1b pathway in porcine granulosa cells†.
1/2020	FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway.
1/2020	The FSH-HIF-1α-VEGF Pathway Is Critical for Ovulation and Oocyte Health but Not Necessary for Follicular Growth in Mice.
1/2018	Hypoxia-inducible factor-1α-dependent autophagy plays a role in glycolysis switch in mouse granulosa cells.
1/2017	Administration of follicle-stimulating hormone induces autophagy via upregulation of HIF-1α in mouse granulosa cells.
1/2016	MicroRNA let-7g regulates mouse granulosa cell autophagy by targeting insulin-like growth factor 1 receptor.

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Wang Yao Research Topics

Disease

24	Neoplasms (Cancer) 12/2022 - 01/2014
13	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 10/2014
7	Hypoxia (Hypoxemia) 02/2022 - 01/2016
3	Keratitis 01/2022 - 11/2019
3	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2018
3	Thrombosis (Thrombus) 01/2019 - 12/2015
3	Hemorrhage 02/2018 - 01/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2021 - 12/2018
2	Premature Birth (Birth, Premature) 06/2015 - 06/2014
1	Triple Negative Breast Neoplasms 12/2022
1	Birth Weight (Birth Weights) 06/2022
1	Corneal Diseases (Corneal Disease) 01/2022
1	Disease Progression 01/2022
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2022
1	Esophageal Squamous Cell Carcinoma 10/2021
1	Female Infertility 10/2021
1	Pathologic Processes 09/2021
1	Lung Neoplasms (Lung Cancer) 07/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021
1	Colonic Neoplasms (Colon Cancer) 12/2020
1	Fibrosarcoma 01/2020
1	Liver Neoplasms (Liver Cancer) 12/2019
1	Keratoconus 11/2019
1	Congenital Abnormalities (Deformity) 11/2019
1	Necrosis 01/2019
1	Pain (Aches) 12/2018
1	Poisoning 11/2018

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 09/2021 - 01/2016
3	Glutathione (Reduced Glutathione)IBA 02/2022 - 07/2021
3	Sorafenib (BAY 43-9006)FDA Link 01/2020 - 09/2015
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2015
2	1-phenyl-3,3-dimethyltriazene (PDT)IBA 02/2022 - 03/2021
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 12/2019
2	MicroRNAs (MicroRNA)IBA 10/2021 - 07/2015
2	MetalsIBA 11/2018 - 08/2016
2	OligosaccharidesIBA 06/2018 - 01/2018
2	AnticoagulantsIBA 02/2018 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 01/2015
2	Hydrochloric Acid (Hydrogen Chloride)FDA Link 01/2017 - 10/2014
1	LipidsIBA 06/2022
1	ProdrugsIBA 02/2022
1	AntioxidantsIBA 02/2022
1	Dendrimers (Dendrons)IBA 02/2022
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2022
1	Interleukin-10 (Interleukin 10)IBA 01/2022
1	Contrast MediaIBA 01/2022
1	Octreotide (Sandostatin)FDA LinkGeneric 01/2022
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022
1	CytokinesIBA 01/2022
1	4-trifluoromethylsalicylic acid (HTB)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 10/2021
1	Biomarkers (Surrogate Marker)IBA 10/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 07/2021
1	Folic Acid (Vitamin M)FDA LinkGeneric 07/2021
1	Artificial ReceptorsIBA 03/2021
1	AminesIBA 03/2021
1	AzidesIBA 03/2021
1	phytochlorinIBA 03/2021
1	Photosensitizing Agents (Photosensitizers)IBA 03/2021
1	Small Interfering RNA (siRNA)IBA 01/2021
1	Capecitabine (Xeloda)FDA Link 12/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2020
1	Phosphotransferases (Kinase)IBA 12/2020
1	cobaltous chloride (cobalt(II)chloride)IBA 12/2020
1	Insulin-Like Growth Factor I (IGF-1)IBA 12/2020
1	CyclinsIBA 12/2020
1	Cyclin EIBA 12/2020
1	Singlet OxygenIBA 02/2020
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020
1	ORALIT (ORS)IBA 01/2020
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2020
1	Nuclear Respiratory Factor 1IBA 01/2020
1	mitochondrial transcription factor AIBA 01/2020
1	PTEN-induced putative kinaseIBA 01/2020
1	Biological ProductsIBA 01/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2019
1	IodineIBA 01/2019
1	metuximabIBA 01/2019
1	apatinibIBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	Therapeutic UsesIBA 12/2018
1	Oxygen (Dioxygen)IBA 11/2018
1	CarbonIBA 11/2018

Therapy/Procedure

9	Therapeutics 12/2022 - 01/2014
3	Corneal Transplantation (Keratoplasty) 01/2022 - 11/2019
3	Drug Therapy (Chemotherapy) 10/2021 - 12/2020
3	Radiofrequency Ablation 01/2018 - 08/2016
3	Stents 11/2017 - 08/2016
2	Immunotherapy 12/2022 - 10/2021
2	Aftercare (After-Treatment) 01/2019 - 01/2014
2	Hysterectomy 06/2015 - 06/2014
1	Photochemotherapy (Photodynamic Therapy) 02/2022
1	Precision Medicine 01/2022
1	Lymph Node Excision (Lymph Node Dissection) 12/2021
1	Combination Drug Therapy (Combination Chemotherapy) 10/2021
1	Phototherapy (Light Therapy) 02/2020
1	Intravenous Injections 02/2020
1	Penetrating Keratoplasty 11/2019